What is the Relationship Between Relaxin and Pregnancy?

p>What is relaxin?around the joint. Under the influence of relaxin the
Relaxin is a pregnancy hormone. It is pro­duced inliga­ments become more supple and pliable,
the early stages of pregnancy by the corpus luteumallowing increased movement which in turn reduces
(the shell of the egg left behind after ovulation), andjoint stability.
then by the placenta from about the twelfth weekWhich joints are most at risk? The symphysis pubis
onwards. This hormone is evident in the body from asand sacroiliac joints of the pelvis are fibrous joints.
early as the second week of pregnancy, when it isVery little space separates the ends of the bones in a
produced in large amounts during the first trimester,fibrous joint, and in a non-pregnant state very limited
then reduces by 20% and continues to be producedmovement, if any, takes place around the joint.
until the birth.Additionally, fibrous joints have no joint cavity and rely
Relaxin affects collagen fibressolely on ligaments for their stability. The resulting
Collagen is the main component of connective tissueincreased range of movement of the symphysis pubis
found in cartilage, tendons and liga­ments. Theand sacroil­iac joints, together with the progressive
stability of all joints is maintained by ligaments whichpres­sure exerted by the growing baby, places
are made up of these dense, fibrous strands ofthese joints in an extremely vulnerable position.
connective tissue. During pregnancy relaxin increasesWhat about the abdominal and pelvic floor muscles?
the water content of collagen fibres, increasing theirCollagen is also found in the connective tissue of the
size and elasticity.abdominal and pelvic floor muscles. This is necessary
What effect does this have on the joints? Ligamentsfor the abdominal muscles to stretch and allow the
are normally inelastic, a quality necessary to maintainuterus to grow out of the abdomen, and for the pelvic
joint stability and prevent unnecessary movementfloor muscles to stretch to deliver the baby.